Scientific journals have very high rejection rates — 75 percent or greater. The transformation of a manuscript into a published paper is a major challenge. Learn the logistics of publishing in scientific journals and approaches for minimizing perils from expert editor Harold Drake, Chair of the Department of Ecological Microbiology at the University of Bayreuth in Germany and Editor-in-Chief of the journal Applied and Environmental Microbiology (AEM). AEM has a broad interdisciplinary profile and is the number one cited journal in microbiology and biotechnology. AEM is published by the American Society for Microbiology (ASM) which publishes many journals in various fields of microbiology, including virology, immunology, and clinical microbiology.